Bristol Myers Touts 5-Year Kidney Cancer Data For Opdivo-Yervoy Combo Therapy

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  • Bristol Myers Squibb Co BMY announced Opdivo (nivolumab) plus Yervoy (ipilimumab) long-term survival data in patients with previously untreated advanced or metastatic renal cell carcinoma (RCC).
  • Data were presented at the European Society for Medical Oncology Virtual Congress 2021 (ESMO21).
  • Related Link: Bristol Myers' Immunotherapy Combo Shows Durable Survival At Three Years In MPM Setting.
  • The Phase 3 CheckMate-214 trial showed a five-year survival rate of 48% and 37% for those receiving sunitinib.
  • After a median follow-up of 67.7 months, patients on the dual immunotherapy lived a median of 47 months versus 26.6 months for Pfizer Inc's PFE targeted therapy Sutent (sunitinib).
  • Opdivo plus Yervoy continued to show a higher ORR (39% vs. 32%) and complete response rate than sunitinib (12% vs. 3%). 
  • Also, more patients treated with the combination achieved complete responses and subsequently did not progress (9.6% vs. 2.4%).
  • The safety profile of Opdivo plus Yervoy was manageable.
  • Related: Bristol Myers Scores FDA Approval For Opdivo In Postsurgery Bladder Cancer.
  • Price Action: BMY stock is down 1.66% at $60.97 during the market session on the last check Thursday.
  • Check out our coverage of the European Society for Medical Oncology Congress (ESMO21)
Posted In: BiotechNewsHealth CareGeneralBriefsESMO21Phase 3 Trialrenal cell carcinoma
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